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dramatic treatment effect

— Treatment effect that is so large that it is unlikely to be explained away by bias, even without having been tested in a study designed to minimize bias

Full explanation:

Dramatic treatment effects are so obvious that carefully controlled research is unnecessary, and would usually be regarded as unethical. People may have different definitions of "dramatic" effects.

Example:

Examples of dramatic effects include insulin for diabetes, defibrillation for heart attacks, and drainage of an abscess.

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